2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. HCN Channel
  5. HCN Channel Modulator

HCN Channel Modulator

HCN Channel Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-182459
    Org 34167 (freebase)
    		Modulator
    Org 34167 freebase is a blood-brain barrier permeable HCN channel modulator. Org 34167 freebase possesses high Caco-2 cell permeability. Org 34167 freebase modulates HCN channel function to alter activation properties and suppress neuronal hyperexcitability. Org 34167 freebase induces tremors in mice at specific doses. Org 34167 freebase acts as a research tool for studies on developmental and epileptic encephalopathies as well as depression.